IUI Treatment

GENTLE FIRST-LINE FERTILITY CARE

Precision-Timed IUI Treatment: Designed Around Your Natural Cycle

Intrauterine Insemination (IUI) is one of the most trusted and gentle first-line fertility treatments: simple, minimally invasive, and remarkably effective when timed with precision. Our clinical approach coordinates close follicular ultrasound tracking with laboratory-grade sperm preparation to place healthy, active sperm directly into the uterus at peak ovulation. Every step, from your initial consultation to clinical pregnancy confirmation, is guided by Dr. Devkriti Tiwari Dhirawani with transparent, compassionate care.

Direct Uterine Placement
Density-Gradient Washing
15–20 Min Outpatient
Zero Anaesthesia Needed
Intrauterine Insemination IUI Medical Procedure Diagram
Direct Placement
15–20 Mins
Painless
FIRST-LINE FERTILITY OPTION

What is IUI?

Prepared and concentrated sperm is placed directly into the uterus near ovulation, bypassing vaginal barriers and significantly shortening the sperm's journey to the fallopian tubes.

3–4 Cycles
RECOMMENDED ATTEMPTS

Optimal Trial Window

Clinical evidence demonstrates that most successful IUI conceptions occur within the first 3 to 4 treatment cycles before reassessing and recommending IVF.

IUI Success Rate by Cycle Number

15%
Cycle 1
18%
Cycle 2
20%
Cycle 3
<8%
Cycle 4+

When Is IUI Recommended?

IUI is commonly recommended for individuals and couples facing any of the following fertility challenges:

01
Unexplained Infertility

No specific barrier is identified after comprehensive hormonal, tubal, and semen diagnostics.

02
Mild Male Factor Infertility

Borderline sperm count, reduced motility, or volume challenges successfully resolved by laboratory washing.

03
Cervical Factor Infertility

Thick, acidic, or hostile cervical mucus that hinders or prevents natural sperm passage.

04
Ovulation Disorders & PCOS

Irregular or absent ovulation cycles treated with mild stimulation medication and ultrasound tracking.

05
Mild Endometriosis

Stage I or II pelvic endometriosis with patent fallopian tubes seeking non-invasive initial care.

The IUI Journey: Five Precisely Timed Steps

Ovulation Induction

Targeted medication stimulates the development of healthy, mature eggs, improving the odds of successful fertilization.

01
02
Ovulation Tracking

Regular transvaginal ultrasounds monitor follicle growth. Once maturity is confirmed, a trigger injection is administered to time ovulation precisely.

Semen Preparation

Roughly 24 to 40 hours after the trigger shot, a semen sample is collected and processed in the lab to isolate the healthiest, most motile sperm.

03
04
Insemination

Using a thin, flexible catheter, the prepared sperm is placed directly into the uterus during the fertile window in a quick, virtually painless procedure.

Pregnancy Test

Approximately two weeks after insemination, a sensitive blood serum beta-hCG test confirms the clinical outcome of the cycle.

05
IUI Laboratory Sperm Processing and Fertilization Mechanism
ANDROLOGY LAB SCIENCE
Sperm Pellet Preparation

Centrifugation separates active sperm for direct uterine access.

How Sperm Washing Maximizes Natural Conception

Natural semen contains prostaglandins, leukocytes, and non-motile cells that can cause uterine cramping. Our specialized laboratory preparation refines the sample into pure, hyperactive sperm:

Density Gradient Centrifugation

Separates debris and immotile sperm, concentrating the most motile, morphologically ideal sperm cells into a purified pellet.

Direct Fallopian Access

Bypasses the acidic vaginal environment and cervical barrier, shortening the travel distance from 18 centimeters to millimeters.

Synchronized Ovulation Timing

Insemination occurs within 24 to 36 hours of the LH surge or hCG trigger, placing sperm exactly as the oocyte enters the tube.

Success Rates and Key Clinical Factors

IUI success varies cycle to cycle, shaped by key biological factors:

Age of the Woman

Younger patients generally achieve higher per-cycle success due to robust ovarian reserve and egg quality.

Underlying Cause of Infertility

Unexplained subfertility and mild male-factor cases show the highest response rates to timed IUI.

Number of Treatment Cycles

Cumulative success typically rises across repeated cycles, with highest efficacy observed across 3 to 4 attempts.

Controlled Ovarian Stimulation

Mild oral or injectable stimulation optimizes the maturation of 1 to 2 follicles without hyperstimulation risk.

Typical Success Rate Bands by Patient Profile
15–25%
Age Under 35
10–15%
Age 35 to 40
< 10%
Age Above 40
15–20%
Average Per Cycle

*Individual results depend on diagnostic evaluation and cycle response.

Why Choose Our Centre for IUI

Our dedicated fertility specialists combine evidence-based clinical protocols with compassionate, patient-first care.

01
Expertise and Experience

A specialist-led team with an established track record in successful IUI cycles and gentle patient care.

02
Personalized Treatment Plans

Every protocol is tailored to the individual's hormonal profile and cycle history for maximum comfort and success.

03
Comprehensive Fertility Services

Full spectrum of care, from diagnostic workup to advanced IVF and ICSI if needed, all under one roof.

04
State of the Art Facility

Modern andrology lab and high-resolution ultrasound equipment supporting ultra-precise insemination timing.

05
Patient-Centered Approach

Compassionate, transparent support throughout the fertility journey with round-the-clock guidance and emotional care.

IUI vs IVF: Comparing Your Treatment Options

IUI is often the first-line assisted reproductive treatment. Understanding how it compares to IVF helps couples and doctors decide the optimal path for their specific fertility profile.

Feature IUI Treatment IVF / ICSI Treatment
Clinical Process Washed, concentrated sperm placed directly into uterus Eggs and sperm fertilized in Class 10,000 embryology lab
Complexity Gentle, minimally invasive outpatient procedure Multi-step advanced laboratory and stimulation process
Cost Profile Economical and accessible first-line option Higher investment for advanced embryology culture
Procedure Duration 15 to 20 minute quick office procedure Comprehensive 4 to 6 week cycle
Ideal Candidates Mild male factor, young couples, unexplained infertility Tubal blockage, severe male factor, failed IUI, low AMH
Success Rate 15 to 20% per cycle 60 to 75% cumulative per cycle
Anaesthesia Required None required Light sedation for egg retrieval only

When to transition from IUI to IVF: If IUI does not result in pregnancy after 3 to 4 well-monitored cycles (or fewer if maternal age is above 35 or severe factor is present), doctors recommend transitioning to IVF, which offers significantly higher success rates. Dr. Devkriti will review your cycle data and provide honest guidance.

Learn About Advanced Embryology & ICSI

Frequently Asked Questions About IUI

The success rate of IUI averages 15 to 20% per cycle for eligible couples under 35. Cumulative success across 3 treatment cycles reaches 40 to 50%, influenced by maternal age, sperm count, and tubal health.

IUI is generally painless. Most women describe it as similar to a routine Pap smear, with mild transient cramping during catheter passage. No anaesthesia is needed and patients walk out immediately.

IUI is timed precisely around ovulation, typically performed 24 to 36 hours after an ovulation trigger injection to ensure sperm is present in the uterus right when the egg is released.

While natural cycle IUI is possible, mild oral medications or low-dose injections are often recommended to stimulate the maturation of 1 or 2 healthy eggs and optimize fertilization timing.

You can resume daily routine activities immediately after resting for 15 to 20 minutes at the clinic. We recommend avoiding heavy weightlifting or high-impact workouts for 48 hours.

If pregnancy is not achieved after 3 to 4 attempts, Dr. Devkriti will review your diagnostic markers and guide you toward advanced options like IVF or ICSI, which offer 60 to 75% cumulative success rates.

Risks are very low: mild cramping, rare minor spotting, and a slight chance of multiple pregnancy if stimulating medication produces more than one mature egg. Regular ultrasound tracking minimizes these risks.